Azithromycin in a single oral 1-g dose is now a recommended regimen of Common STDs: Part I. Herpes, Syphilis, Urethritis, Chlamydia and Gonorrhea 1 g of oral azithromycin and 250 mg of intramuscular ceftriaxone, are.
Dual therapy with ceftriaxone and azithromycin remains the only recommended first-line regimen for the treatment of gonorrhea in the United States. The ceftriaxone kills the gonorrhea bacteria and is boosted by the The azithromycin or doxycycline knocks out the chlamydia bacteria. The CDC currently recommends dual treatment with ceftriaxone and azithromycin for most gonococcal infections. Multidrug-resistant gonorrhea. Dual antimicrobial therapy (ceftriaxone plus azithromycin) is a recommended treatment failure with dual therapy in a patient with gonorrhea. Those with infection of the pharynx may be treated with Ceftriaxone 500 mg IM with azithromycin 1 g orally as a single dose or may be given.