Learn about drug interactions between fluoxetine oral and sumatriptan-naproxen oral and use the RxList drug interaction checker to check drug combinations. Of 22 adverse event reports obtained six showed varying degrees of evidence of a drug interaction between fluoxetine and sumatriptan, suggesting that this. In Ms. B's case, agents inhibiting 5-HT reuptake (fluoxetine and amitriptyline) were combined with a direct 5-HT agonist (sumatriptan).
The resulting potentiation. Acta Psychiatr Scand. 1997 Jun;95(6):551-2. Co-administration of fluoxetine and sumatriptan: the Canadian experience. Joffe RT(1), Sokolov ST. Using FLUoxetine together with SUMAtriptan can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms. Imitrex [sumatriptan] • Maxalt [rizatriptan] • Relpex [eletriptan] • Treximet [sumatriptan and naproxen combination] Prozac [fluoxetine].