ELI5: The difference between Advil, Tylenol, Motrin, Ibuprofen, Advil & Motrin = Ibuprofen Tylenol = Acetominophen Aspirin = ASA (acetyl. Motrin, Aleve, Tylenol, and Ecotrin are pain relievers we commonly find on drugstore Is There Any Difference Between OTC Pain Relievers?
Acetaminophen Brand name: Tylenol Best for: Excellent for pain relief Pain relievers: What are the differences? Brand names: Motrin, Advil. In addition to reducing fever, body aches, and pain caused by prostaglandins, ibuprofen reduces inflammation (swelling and redness). It's slightly more powerful and longer lasting than acetaminophen. Because of this, it can be taken only every six to eight hours and no more than three times in a 24-hour period. The active ingredient in MOTRIN® products is ibuprofen (a nonsteroidal anti-inflammatory drug, or NSAID).
MOTRIN® products don't contain acetaminophen, the active ingredient in TYLENOL® products. Each of these ingredients relieves pain and reduces fever, but they work differently.