Once reserved solely as a treatment for metastatic prostate cancer, hormone The drug most often used is bicalutamide, which is given once a day and is less. Bicalutamide in Advanced. Prostate Cancer. A Review. Karen L. Goa and Caroline M. Spencer. Adis International Limited, Auckland, New Zealand. Various. Bicalutamide is a non-steroidal anti-androgen used to treat advanced (metastatic) prostate cancer. It works by reducing the amount of testosterone in the body. Adding bicalutamide improves overall survival among patients with advanced nonmetastatic hormone-naïve prostate cancer.
Bicalutamide, flutamide, and nilutamide work by blocking testosterone's palliative benefit to men with advanced prostate cancer; docetaxel (Taxotere) was. Bicalutamide therapy is for men with advanced prostate cancer at stage D2, when there is evidence of metastases (cancer spread) to other areas of the body.
Bicalutamide is also used to treat prostate cancer that has spread to other parts of the body (advanced prostate cancer). Bicalutamide may be given after surgery.